Lactosylceramide (LacCer), synthesized from beta-glucosylceramide by lactosylceramide synthase in the Golgi, is a ubiquitous sphingolipid in mammalian tissue. Lactosylceramide is important in many cellular functions such as cell proliferation, migration, adhesion, and angiogenesis. Increased production of LacCer have been shown to increase levels of reactive oxygen species in cardiomyocites and are implicated in inflammatory pathways. Biotin-Lactosylceramide can be bound to streptavidin coated surfaces such as plates or beads.
