Fluorescein conjugated Anti-PI(4,5)P2 IgM

Artikelnummer: ECH-Z-G045
Artikelname: Fluorescein conjugated Anti-PI(4,5)P2 IgM
Artikelnummer: ECH-Z-G045
Hersteller Artikelnummer: Z-G045
Alternativnummer: ECH-Z-G045-10UG, ECH-Z-G045-50UG, ECH-Z-G045-5X50UG
Hersteller: Echelon Biosciences
Kategorie: Molekularbiologie
Purified Anti-PtdIns(4,5)P2 monoclonal antibody conjugated with fluorescein. Subclass: IgM Source: Mouse Applications: ELISA, Immunofluorescence Concentration: 0.5 - 1 mg/mL depending on lot number. Please see lot specific TDS.
Product Background: Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PIP3.

Storage

Protect from light. 2-8 C for up to 30 days, -20 C for greater than 30 days. Do not freeze thaw multiple times

Featured in Publications

1) Antony, P., K. Hoek, et al. (2007). Micro-scale flow cytometry-based and biochemical analysis of lipid signaling in primary B cell subpopulations. Biol Proced Online 9: 73-83. 2) Heuvingh, J., M. Franco, et al. (2007). ARF1-mediated actin polymerization produces movement of artificial vesicles. Proc Natl Acad Sci U S A 104(43): 16928-33. Product keywords: PIP2, PI(4,5)P2, PtdIns(4,5)P2, IgM, anti-PIP2

Documents

Technical Data Sheet
Anwendungsbeschreibung: Categories: Antibodies & Proteins. Related: Antibody, Fluorescent, Lipid Binding, PI(4\,5)P2. Ship 1 : Shipping Temp. Ship 2: Dry Ice