Purified Anti-Lysophosphatidic Acid (LPA) monoclonal antibody.Subclass: IgGk1Source: MouseApplications: ELISA Immunohistochemistry ImmunocytochemistryProduct Background: Lysophosphatidic Acid (LPA) is a serum-derived phospholipid involved in diverse cellular processes such as cell proliferation chemotaxis platelet aggregation wound healing angiogenesis tumor invasion and smooth muscle contraction. Recent research indicates LPA may play a significant role in the pathophysiology of cancer and may be used as a biomarker for ovarian cancer. The Lysophosphatidic Acid Antibody (504B3) was originally developed and patented at Lpath Therapeutics.StorageAntibody is stable for up to 1 year at -20 AC. Antibody is stable for 60 days at 4AC. Avoid repeated freeze/thaw cycles. Powered by Bioz See more details on BiozReferences1) J. Cheng S. Sahani T.J. Hausrat et al. (2016) Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling Neuron 92(1), 126-142. doi: doi:10.1016/j.neuron.2016.08.0352) M. Balood H. Zahednasab et al. (2014) Elevated serum levels of lysophosphatidic acid in patients with multiple sclerosis Hum. Immunol. 75(5), 411-413 doi: 10.1016/j.humimm.2014.02.0213) Y. Goldshmit R. Matteo et al. (2012) Blockage of lysophosphatidic acid signaling improves spinal cord injury outcomes. Am. J. Pathol. 181(3): 978-992 doi: 10.1016/j.ajpath.2012.06.007Bulk discounts available please email echelon echelon-inc.com for information.
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