JAK2 (6B4) Mouse Monoclonal Antibody, IgG1, Unconjugated

Produktübersicht

• Artikelname: JAK2 (6B4) Mouse Monoclonal Antibody, IgG1, Unconjugated
• Artikelnummer: EKL-AMM00767
• Hersteller Artikelnummer: AMM00767
• Alternativnummer: EKL-AMM00767-50UL,EKL-AMM00767-100UL,EKL-AMM00767-500UL,EKL-AMM00767-200UL
• Hersteller: EnkiLife
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC-P
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: JAK2, Tyrosine-protein kinase JAK2, Janus kinase 2, JAK-2

Produktbeschreibung

Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.

Produkteigenschaften

• Klonalität: Monoclonal
• Isotyp: IgG1
• NCBI: 3717
• UniProt: O60674
• Puffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: JAK2

Anwendungsbeschreibung

• Application Verdünnung: IHC: 1:50-1:100