JNK1 (1A4) Mouse Monoclonal Antibody, IgG2a, Unconjugated

Produktübersicht

• Artikelname: JNK1 (1A4) Mouse Monoclonal Antibody, IgG2a, Unconjugated
• Artikelnummer: EKL-AMM03520
• Hersteller Artikelnummer: AMM03520
• Alternativnummer: EKL-AMM03520-50UL,EKL-AMM03520-100UL,EKL-AMM03520-500UL,EKL-AMM03520-200UL
• Hersteller: EnkiLife
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ICC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: AI849689, c Jun N terminal kinase 1, C-JUN kinase 1, c-Jun N-terminal kinase 1, EC 2.7.11.24, JAK 1A, JAK1A, JNK 1, JNK 46, JNK, JNK-46, JNK1A2, JNK21B1/2, MAP kinase 8, MAPK 8, MAPK8, Mitogen activated protein kinase 8, Mitogen-activated protein kinase 8, MK08_HUMAN, p54 gamma, PRKM 8, PRKM8, Protein kinase JNK1, Protein kinase, mitogen-activated, 8, SAPK 1, SAPK gamma, SAPK1, Stress activated protein kinase JNK1, Stress-activated protein kinase 1, Stress-activated protein kinase JNK1, Tyrosine protein kinase JAK1 .

Produktbeschreibung

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: Calculated MW: 48 kDa, Observed MW: 46,54 kDa
• Isotyp: IgG2a
• NCBI: 5599
• UniProt: P45983
• Puffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: MAPK8

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:500-1:1000 IF: 1:50-1:200