XRCC4 (7C10) Mouse Monoclonal Antibody, IgG1, Unconjugated

Produktübersicht

• Artikelname: XRCC4 (7C10) Mouse Monoclonal Antibody, IgG1, Unconjugated
• Artikelnummer: EKL-AMM03579
• Hersteller Artikelnummer: AMM03579
• Alternativnummer: EKL-AMM03579-50UL,EKL-AMM03579-100UL,EKL-AMM03579-500UL,EKL-AMM03579-200UL
• Hersteller: EnkiLife
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ICC, IHC-Fr, IHC-P, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: X ray repair cross complementing protein 4, DNA repair protein XRCC4, DNA double strand break repair

Produktbeschreibung

Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: Calculated MW: 38 kDa, Observed MW: 38-45 kDa
• Isotyp: IgG1
• NCBI: 7518
• UniProt: Q13426
• Puffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: XRCC4

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20