PI3 Kinase p85 alpha (3H5) Mouse Monoclonal Antibody, IgG1, Unconjugated

Produktübersicht

• Artikelname: PI3 Kinase p85 alpha (3H5) Mouse Monoclonal Antibody, IgG1, Unconjugated
• Artikelnummer: EKL-AMM03618
• Hersteller Artikelnummer: AMM03618
• Alternativnummer: EKL-AMM03618-50UL,EKL-AMM03618-100UL,EKL-AMM03618-500UL,EKL-AMM03618-200UL
• Hersteller: EnkiLife
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: PIK3R1, GRB1, Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha

Produktbeschreibung

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: Calculated MW: 84 kDa, Observed MW: 84 kDa
• Isotyp: IgG1
• NCBI: 5295
• UniProt: P27986
• Puffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: PIK3R1

Anwendungsbeschreibung

• Application Verdünnung: WB: 1:500-1:1000 IHC: 1:50-1:100