BCL-10 Mouse Monoclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: BCL-10 Mouse Monoclonal Antibody, Unconjugated
• Artikelnummer: EKL-AMM80502
• Hersteller Artikelnummer: AMM80502
• Alternativnummer: EKL-AMM80502-50UL,EKL-AMM80502-100UL
• Hersteller: EnkiLife
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ELISA, FC, ICC, IHC, WB
• Spezies Reaktivität: Human, Mouse
• Konjugation: Unconjugated
• Alternative Synonym: CLAP, Me10, CIPER, c-E10, CARMEN

Produktbeschreibung

Bcl-10 (B-cell CLL/lymphoma 10), also known as CLAP, Me10, CIPER, c-E10, CARMEN. Entrez Protein NP_003912. It is a protein containing a caspase recruitment domain (CARD). It plays an important
role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other
CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as
upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which
encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to
synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to
the same pathogenetic process that leads to the malignancy.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 26kDa
• NCBI: 8915
• UniProt: O95999
• Puffer: Ascitic fluid containing 0.03% sodium azide.
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: BCL-10

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-1:2000,IHC 1:200-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400