MAP2K4 Mouse Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMM80564
Artikelname: MAP2K4 Mouse Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMM80564
Hersteller Artikelnummer: AMM80564
Alternativnummer: EKL-AMM80564-50UL,EKL-AMM80564-100UL
Hersteller: EnkiLife
Wirt: Mouse
Kategorie: Antikörper
Applikation: ELISA, IHC
Spezies Reaktivität: Human
Konjugation: Unconjugated
Alternative Synonym: MAP2K4
MAP2K4(mitogen-activated protein kinase kinase 4), which is located on chromosome 17p11.2, with 399-amino acid protein (about 45 kDa), belongs to the family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. MEK-4 (also called MEK4/MKK4) activates both p38 and JNK MAP kinases.
MKK4 is a central mediator in the stress activated protein kinase signaling pathway that responds to a number of cellular and environmental stressors. By phosphorylating MAP kinases such as JNK,MKK4 can ultimately transmit stress signals to nuclear transcription factors that mediate various processes including proliferation, apoptosis, and differentiation. Its distinct biological functions have been identified for MKK4 including a role in development, hepatogenesis, and metastasis suppression.
Klonalität: Monoclonal
Molekulargewicht: /
NCBI: 6416
UniProt: P45985
Puffer: Ascitic fluid containing 0.03% sodium azide.
Reinheit: Affinity Purification
Formulierung: Liquid
Target-Kategorie: MAP2K4
Application Verdünnung: IHC 1:200-1:1000,ELISA 1:5000-1:20000