Gli1 (17P5) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE11461
Produktübersicht
Artikelname:
Gli1 (17P5) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE11461
Hersteller Artikelnummer:
AMRe11461
Alternativnummer:
EKL-AMRE11461-50UL, EKL-AMRE11461-100UL, EKL-AMRE11461-200UL
Hersteller:
EnkiLife
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human
Konjugation:
Unconjugated
Alternative Synonym:
Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLI, Zfp5, GLI family zinc finger 1,GLI,
Produktbeschreibung
GLI belongs to the Kruppel family of zinc finger proteins that includes three mammalian GLI proteins: GLI1, GLI2, and GLI3. Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation. Acts as a transcriptional activator (PubMed:19706761, PubMed: 10806483, PubMed: 19878745, PubMed: 24076122, PubMed: 24311597, PubMed: 24217340). Binds to the DNA consensus sequence 5-GACCACCCA-3 (PubMed: 2105456, PubMed: 8378770, PubMed: 24217340). Regulates the transcription of specific genes during normal development (PubMed: 19706761). Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling (PubMed: 19706761, PubMed: 28973407). Plays a role in cell proliferation and differentiation via its role in SHH signaling (PubMed: 11238441, PubMed: 28973407).
Produkteigenschaften
Klonalität:
Monoclonal
Molekulargewicht:
118kDa
NCBI:
2735
UniProt:
P08151
Puffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit:
Affinity purification
Formulierung:
Liquid
Target-Kategorie:
GLI1
Anwendungsbeschreibung
Application Verdünnung:
WB 1:500-1:2000
