GRSF1 (18C16) Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer:
EKL-AMRE11803
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| Artikelname: | GRSF1 (18C16) Rabbit Monoclonal Antibody, Unconjugated |
| Artikelnummer: | EKL-AMRE11803 |
| Hersteller Artikelnummer: | AMRe11803 |
| Alternativnummer: | EKL-AMRE11803-50UL, EKL-AMRE11803-100UL, EKL-AMRE11803-200UL |
| Hersteller: | EnkiLife |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | FC, ICC, IP, WB |
| Spezies Reaktivität: | Human, Mouse, Rat |
| Konjugation: | Unconjugated |
| Alternative Synonym: | GRSF1, |
| Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G-rich element. Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G- rich element. Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences (PubMed:23473033, PubMed:23473034, PubMed:29967381). Involved in the degradosome-mediated decay of non- coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules (PubMed:29967381). Acts by unwinding G-quadruplex RNA structures in MT- ncRNA, thus facilitating their degradation by the degradosome (PubMed:29967381). G-quadruplexes (G4) are non-canonical 4 stranded structures formed by transcripts from the light strand of mtDNA (PubMed:29967381). |
| Klonalität: | Monoclonal |
| Molekulargewicht: | 53kDa |
| NCBI: | 2926 |
| UniProt: | Q12849 |
| Puffer: | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle. |
| Reinheit: | Affinity purification |
| Formulierung: | Liquid |
| Target-Kategorie: | GRSF1 |
| Application Verdünnung: | WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:50-1:200,IP 1:50-1:100 |
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