Integrin alpha 6 (19T9) Rabbit Monoclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: Integrin alpha 6 (19T9) Rabbit Monoclonal Antibody, Unconjugated
• Artikelnummer: EKL-AMRE12651
• Hersteller Artikelnummer: AMRe12651
• Alternativnummer: EKL-AMRE12651-50UL, EKL-AMRE12651-100UL, EKL-AMRE12651-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IF, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: ITGA6, CD49 antigen-like family member F, VLA-6, CD49f,

Produktbeschreibung

Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets (By similarity). Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion (By similarity). Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 127kDa
• NCBI: 3655
• UniProt: P23229
• Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
• Reinheit: Affinity purification
• Formulierung: Liquid
• Target-Kategorie: ITGA6

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-1:2000,IHC 1:200-1:500,IF-P 1:200-1:500