MEIS proteins belong to the TALE (Three Amino Acid Loop Extension) homeobox containing transcription factor family. MEIS1 has been associated with leukemogenesis and neuroblastoma. Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
Reinheit:
Affinity purification
Formulierung:
Liquid
Target-Kategorie:
MEIS1
Application Verdünnung:
WB 1:2000-1:20000,IP 1:10-1:100
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