PMP70 (6N3) Rabbit Monoclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: PMP70 (6N3) Rabbit Monoclonal Antibody, Unconjugated
• Artikelnummer: EKL-AMRE16310
• Hersteller Artikelnummer: AMRe16310
• Alternativnummer: EKL-AMRE16310-50UL, EKL-AMRE16310-100UL, EKL-AMRE16310-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, ICC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: ABCD3, ABC43, PMP70, PXMP1, ZWS2,

Produktbeschreibung

Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity. Broad substrate specificity ATP-dependent transporter of the ATP-binding cassette (ABC) family that catalyzes the transport of long- chain fatty acids (LCFA)-CoA, dicarboxylic acids-CoA, long-branched- chain fatty acids-CoA and bile acids from the cytosol to the peroxisome lumen for beta-oxydation (PubMed:11248239, PubMed:25168382, PubMed:24333844, PubMed:29397936). Has fatty acyl-CoA thioesterase and ATPase activities (PubMed:29397936). Probably hydrolyzes fatty acyl- CoAs into free fatty acids prior to their ATP-dependent transport into peroxisomes (By similarity). Thus, play a role in regulation of LCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation (PubMed:25944712, PubMed:24333844).

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 76kDa
• NCBI: 5825
• UniProt: P28288
• Puffer: Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
• Reinheit: Affinity purification
• Formulierung: Liquid
• Target-Kategorie: ABCD3

Anwendungsbeschreibung

• Application Verdünnung: WB 1:1000-1:5000,ICC/IF 1:100-1:200,FC 1:100-1:500