Prolactin Receptor (2K9) Rabbit Monoclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: Prolactin Receptor (2K9) Rabbit Monoclonal Antibody, Unconjugated
• Artikelnummer: EKL-AMRE16522
• Hersteller Artikelnummer: AMRe16522
• Alternativnummer: EKL-AMRE16522-50UL, EKL-AMRE16522-100UL, EKL-AMRE16522-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ICC, IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: CPRLP, HPRL, hPRL receptor, Lactogen receptor, MFAB, OPR, Pr-1, Pr-3, PRLR, Prolactin receptor a,

Produktbeschreibung

Activate multiple signal transduction pathways in breast cancer cells, including the Jak/Stat, PI3K/Akt, and MAPK pathways, leading to both pro-proliferative and anti-apoptotic downstream effects. This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.

Produkteigenschaften

• Klonalität: Monoclonal
• Molekulargewicht: 70kDa
• NCBI: 5618
• UniProt: P16471
• Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
• Reinheit: Affinity purification
• Formulierung: Liquid
• Target-Kategorie: PRLR

Anwendungsbeschreibung

• Application Verdünnung: WB 1:1000-1:5000,IHC 1:50-1:100,ICC/IF 1:100-1:200