NOS2,NOS2A,Nitric oxide synthase,inducible,Hepatocyte NOS,HEP-NOS,Inducible NO synthase,Inducible NOS,iNOS,NOS type II,Peptidyl-cysteine S-nitrosylase NOS2
Cell localization:Cytoplasm, cytosol . Localizes as discrete foci scattered throughout the cytosol and in the presence of SPSB1 and SPSB4, exhibits a more diffuse cytosolic localization. ..Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, JµL 2008],