DNase IV, FEN1, Flap endonuclease 1, Flap structure specific endonuclease 1, hFEN-1, hFEN1, Maturation factor 1, MF1, Rad2,,FEN1
Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5-3 exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
