Homer, HOMER 1A, HOMER 1B, HOMER 1C, homer homolog 1, Homer1, HOMER1A, HOMER1B, HOMER1C, SYN47,,Homer 1
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2.
