3 keto acyl CoA synthase ELOVL5, Elongation of very long chain fatty acids like 5, ELOVL 5, ELOVL family member 5, ELOVL family member 5 elongation of long chain fatty acids, ELOVL fatty acid elongase 5, ELOVL2, elovl5, Fatty acid elongase 1, hELO1, RP3 483K16.1, RP3-483K16.1, ,ELOVL5
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.
