EAAT2 Rabbit Monoclonal Antibody, Unconjugated

Artikelnummer: EKL-AMRE86785
Artikelname: EAAT2 Rabbit Monoclonal Antibody, Unconjugated
Artikelnummer: EKL-AMRE86785
Hersteller Artikelnummer: AMRe86785
Alternativnummer: EKL-AMRE86785-50UL,EKL-AMRE86785-100UL
Hersteller: EnkiLife
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC, IP, WB
Spezies Reaktivität: Mouse, Rat
Konjugation: Unconjugated
Alternative Synonym: GLT1, Eaat2, GLT-1, MGLT1, AI159670, 1700091C19Rik, 2900019G14Rik
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7698742, PubMed:7557442, PubMed:9373176). Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport, this avoids the accumulation of negative charges due to aspartate and Na+ symport (By similarity). Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate (PubMed:9180080).
Klonalität: Monoclonal
Molekulargewicht: Calculated MW:62 kDa, Observed MW:65 kDa
NCBI: 20511
UniProt: P43006
Puffer: Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Reinheit: Affinity Purification
Formulierung: Liquid
Target-Kategorie: EAAT2
Application Verdünnung: WB 1:500-1:2000,IHC 1:200-1:2000,IP 1:20-1:50