Integrin alpha 5 Rabbit Polyclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: Integrin alpha 5 Rabbit Polyclonal Antibody, Unconjugated
• Artikelnummer: EKL-APRAB00133
• Hersteller Artikelnummer: APRab00133
• Alternativnummer: EKL-APRAB00133-20UL, EKL-APRAB00133-50UL, EKL-APRAB00133-100UL, EKL-APRAB00133-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, ICC, IHC, IP, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: ITGA5, FNRA, Integrin alpha-5, CD49 antigen-like family member E, Fibronectin receptor subunit alpha, Integrin alpha-F, VLA-5, CD49e

Produktbeschreibung

Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: Calculated MW: 115 kDa, Observed MW: 150 kDa
• NCBI: 3678
• UniProt: P08648
• Puffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Reinheit: Affinity Chromatography
• Formulierung: Liquid
• Target-Kategorie: ITGA5

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,FC 1:50-1:100,IP 1:20-1:50