Phospho-IKK alpha (Thr23) Rabbit Polyclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: Phospho-IKK alpha (Thr23) Rabbit Polyclonal Antibody, Unconjugated
• Artikelnummer: EKL-APRAB00914
• Hersteller Artikelnummer: APRab00914
• Alternativnummer: EKL-APRAB00914-20UL, EKL-APRAB00914-50UL, EKL-APRAB00914-100UL, EKL-APRAB00914-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Unconjugated
• Alternative Synonym: CHUK, IKKA, TCF16, Inhibitor of nuclear factor kappa-B kinase subunit alpha, I-kappa-B kinase alpha, IKK-A, IKK-alpha, IkBKA, IkappaB kinase, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, IKK1, Nuclear factor NF-kappa-B

Produktbeschreibung

Plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKKbeta (Ser176 and Ser180 in IKKalpha), which causes conformational changes, resulting in kinase activation.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: Calculated MW: 85 kDa, Observed MW: 85 kDa
• NCBI: 1147
• UniProt: O15111
• Puffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: CHUK

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-1:1000,IHC 1:50-1:100