p21 Rabbit Polyclonal Antibody, Unconjugated

Produktübersicht

• Artikelname: p21 Rabbit Polyclonal Antibody, Unconjugated
• Artikelnummer: EKL-APRAB01362
• Hersteller Artikelnummer: APRab01362
• Alternativnummer: EKL-APRAB01362-20UL, EKL-APRAB01362-50UL, EKL-APRAB01362-100UL, EKL-APRAB01362-200UL
• Hersteller: EnkiLife
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, IHC, IP, WB
• Spezies Reaktivität: Human
• Konjugation: Unconjugated
• Alternative Synonym: CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1, Cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, Melanoma differentiation-associated protein 6, MDA-6, p21

Produktbeschreibung

The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D.

Produkteigenschaften

• Klonalität: Polyclonal
• Molekulargewicht: Calculated MW: 18 kDa, Observed MW: 21 kDa
• NCBI: 1026
• UniProt: P38936
• Puffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Reinheit: Affinity Purification
• Formulierung: Liquid
• Target-Kategorie: CDKN1A

Anwendungsbeschreibung

• Application Verdünnung: WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100,IP 1:20-1:50