AFG3-like protein 2 (EC 3.4.24.-) (Paraplegin-like protein)
This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. [provided by RefSeq, Jul 2008],cofactor:Binds 1 zinc ion per subunit .,function:Putative ATP-dependent protease.,similarity:In the C-terminal section, belongs to the peptidase M41 family.,similarity:In the N-terminal section, belongs to the AAA ATPase family.,tissue specificity:Ubiquitous.,
