AKR1E2, AKR1CL2, AKRDC1, 1, 5-anhydro-D-fructose reductase, AF reductase, Aldo-keto reductase family 1 member C-like protein 2, Aldo-keto reductase family 1 member E2, LoopADR, Testis-specific protein, hTSP
The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],catalytic activity:1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + NADPH.,function:Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones.,similarity:Belongs to the aldo/keto reductase family.,tissue specificity:Testis-specific.,
