RCBTB1, CLLD7, E4.5, RCC1 and BTB domain-containing protein 1, Chronic lymphocytic leukemia deletion region gene 7 protein, CLL deletion region gene 7 protein, Regulator of chromosome condensation and BTB domain-containing protein 1
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008],function:May be involved in cell cycle regulation by chromatin remodeling.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 2 BTB (POZ) domains.,similarity:Contains 6 RCC1 repeats.,tissue specificity:Ubiquitously expressed.,
