DPP7, DPP2, QPP, Dipeptidyl peptidase 2, Dipeptidyl aminopeptidase II, Dipeptidyl peptidase 7, Dipeptidyl peptidase II, DPP II, Quiescent cell proline dipeptidase
The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. [provided by RefSeq, Jul 2008],catalytic activity:Release of an N-terminal dipeptide, Xaa-Yaa-|-, preferentially when Yaa is Ala or Pro. Substrates are oligopeptides, preferentially tripeptides.,function:Plays an important role in the degradation of some oligopeptides.,PTM:N-glycosylated.,similarity:Belongs to the peptidase S28 family.,subunit:Homodimer.,
