KCNF1, Potassium voltage-gated channel subfamily F member 1, Voltage-gated potassium channel subunit Kv5.1, kH1
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008],domain:The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.,function:Putative voltage-gated potassium channel.,similarity:Belongs to the potassium channel family. F subfamily.,subunit:Heteromultimer with KCNG3, KCNG4 and KCNV2. Interacts with DLG1.,tissue specificity:Detected in heart, brain, liver, skeletal muscle, kidney and pancreas.,
