This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq, Sep 2014],function:Chemotactic activity for lymphocytes but not for monocytes or neutrophils.,online information:XCL1 entry,similarity:Belongs to the intercrine gamma family.,tissue specificity:Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.,
