RAB11FIP4, ARFO2, KIAA1821, Rab11 family-interacting protein 4, FIP4-Rab11, Rab11-FIP4, Arfophilin-2
Proteins of the large Rab GTPase family (see RAB1A, MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP4 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Apr 2008],function:A Rab11 effector protein acting in the endosomal trafficking.,similarity:Contains 1 EF-hand domain.,subcellular location:Colocalizes with RAB11A in the endocytic recycling compartment (ERC).,subunit:Homooligomer. Forms an heterooligomeric complex with RAB11FIP2, RAB11FIP3 and RAB11FIP5. Interacts with RAB11A that has been activated by GTP binding.,
