RHOD, ARHD, Rho-related GTP-binding protein RhoD, Rho-related protein HP1, RhoHP1
Ras homolog, or Rho, proteins interact with protein kinases and may serve as targets for activated GTPase. They play a critical role in muscle differentiation. The protein encoded by this gene binds GTP and is a member of the small GTPase superfamily. It is involved in endosome dynamics and reorganization of the actin cytoskeleton, and it may coordinate membrane transport with the function of the cytoskeleton. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],function:Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:In the GTP-bound form, interacts with DIAPH2 isoform 3.,tissue specificity:Heart, placenta, liver, skeletal muscle, and pancreas and, with weaker intensity, in several other tissues.,
