septin 3(SEPT3) Homo sapiens This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],function:Involved in cytokinesis .,induction:Up-regulated during neuronal differentiation.,PTM:Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91.,similarity:Belongs to the septin family.,subcellular location:Localizes in synaptosomes at dendritic synapses of neurons. Localizes within presynaptic terminals of neurons.,subunit:May assemble into a multicomponent structure.,tissue specificity:Brain specific.,
