The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells. [provided by RefSeq, Aug 2016],function:Probable transcription factor that binds to the PU-box, a purine-rich DNA sequence (5-GAGGA[AT]-3) that can act as a lymphoid-specific enhancer.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Binds DNA as a monomer.,tissue specificity:Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.,
