Recombinant Mouse CCL21, E. coli

Artikelnummer: EKL-PEM0263
Artikelname: Recombinant Mouse CCL21, E. coli
Artikelnummer: EKL-PEM0263
Hersteller Artikelnummer: PEM0263
Alternativnummer: EKL-PEM0263-10UG,EKL-PEM0263-50UG,EKL-PEM0263-500UG
Hersteller: EnkiLife
Wirt: E. coli
Kategorie: Proteine/Peptide
Spezies Reaktivität: Mouse
Alternative Synonym: C-C Motif Chemokine 21a, 6Ckine, Beta-Chemokine Exodus-2, Small-Inducible Cytokine A21a, Thymus-Derived Chemotactic Agent 4, TCA4, Ccl21a, Scya21, Scya21a
C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine beta (CC chemokine) family. Mouse CCL21 cDNA encodes a 133 amino acid residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs.
Molekulargewicht: 12.1 KDa
NCBI: 84444
Reinheit: Greater than 95% as determined by reducing SDS-PAGE
Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.