Recombinant Rat HER2 (C-6His), E. coli

Produktübersicht

• Artikelname: Recombinant Rat HER2 (C-6His), E. coli
• Artikelnummer: EKL-PER0337
• Hersteller Artikelnummer: PER0337
• Alternativnummer: EKL-PER0337-10UG,EKL-PER0337-50UG,EKL-PER0337-500UG
• Hersteller: EnkiLife
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Rat
• Alternative Synonym: Receptor tyrosine-protein kinase erbB-2, Epidermal growth factor receptor-related protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, p185erbB2, p185neu, CD340, ERBB2

Produktbeschreibung

ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpression of ErbB2 has been reported associated with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate and ovarian cancers. Rat ERBB2 is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. ErbB2 mediates signalling pathways which involve mitogen-activated protein kinase and phosphatidylinositol-3 kinase, this receptor plays a key role in development, cell proliferation and differentiation.

Produkteigenschaften

• Molekulargewicht: 29.3 KDa
• NCBI: 06494
• Reinheit: Greater than 95% as determined by reducing SDS-PAGE

Anwendungsbeschreibung

• Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.