Recombinant Human BGN (C-6His)

Artikelnummer: EKL-PHH0153
Artikelname: Recombinant Human BGN (C-6His)
Artikelnummer: EKL-PHH0153
Hersteller Artikelnummer: PHH0153
Alternativnummer: EKL-PHH0153-10UG,EKL-PHH0153-50UG,EKL-PHH0153-500UG
Hersteller: EnkiLife
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Alternative Synonym: Biglycan, Bone/Cartilage Proteoglycan I, PG-S1, BGN, SLRR1A
Biglycan is a 200-350 kD proteoglycan consisting of a 45 kD core protein and two chrondroitin/dermatan sulfate glycosaminoglycan chains. Biglycan binds to TGF-ß. It also binds to collagen type I in low ionic strength (less than 3 mM phosphate) buffer. At higher ionic strengths, Biglycan does not bind to collagen type I. It enhances the inhibition effect of TGF-ß on osteoclast proliferation at a concentration of 4-20 mg/ml. It also prevents the attachment of CHO cells to fibronectin, with a 50% inhibition at 17-21 mg/ml.
Molekulargewicht: 40.47 KDa
NCBI: 21810
Reinheit: Greater than 95% as determined by reducing SDS-PAGE
Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.