Recombinant Human TRAIL R3 (C-Fc-6His)

Produktübersicht

• Artikelname: Recombinant Human TRAIL R3 (C-Fc-6His)
• Artikelnummer: EKL-PHH0318
• Hersteller Artikelnummer: PHH0318
• Alternativnummer: EKL-PHH0318-10UG,EKL-PHH0318-50UG,EKL-PHH0318-500UG
• Hersteller: EnkiLife
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Alternative Synonym: Tumor Necrosis Factor Receptor Superfamily Member 10C, Antagonist Decoy Receptor for TRAIL/Apo-2L, Decoy TRAIL Receptor Without Death Domain, Decoy Receptor 1, DcR1, Lymphocyte Inhibitor of TRAIL, TNF-Related Apoptosis-Inducing Ligand Receptor 3, TRAIL Receptor 3, TRAIL-R3, TRAIL Receptor Without an Intracellular Domain, CD263, TNFRSF10C, DCR1, LIT, TRAILR3, TRID

Produktbeschreibung

Tumor Necrosis Factor Receptor Superfamily Member 10C (TNFRSF10C) is a glycosyl-phosphatidylinositol-linked membrane protein which binds TRAIL with high affinity. TNFRSF10C has the TRAIL-binding extracellular cysteine-rich domains, lacks the intracellular signaling domain. As a result, binding of TRAIL to TRAIL R3 doesnt transduce an apoptosis signal. The expression of TRAIL R3 gene has been shown to protect cells bearing TRAIL R1 and/or TRAIL R2 from TRAIL-induced apoptosis.

Produkteigenschaften

• Molekulargewicht: 48.7 KDa
• NCBI: 14798
• Reinheit: Greater than 95% as determined by reducing SDS-PAGE

Anwendungsbeschreibung

• Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.