Recombinant Human FcRn Heterodimer (C-6His)

Produktübersicht

• Artikelname: Recombinant Human FcRn Heterodimer (C-6His)
• Artikelnummer: EKL-PHH0633
• Hersteller Artikelnummer: PHH0633
• Alternativnummer: EKL-PHH0633-10UG,EKL-PHH0633-50UG,EKL-PHH0633-500UG
• Hersteller: EnkiLife
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Alternative Synonym: IgG receptor FcRn, Neonatal Fc receptor, FCRN

Produktbeschreibung

FcRn complex consist of two subunits: IgG receptor FcRn large subunit p51(alpha chain) and Beta-2-microglobulin(Beta chain). The complexes is similar in structure to MHC class I-like heterodimer. Beta-2-microglobulin involved in the presentation of peptide antigens to the immune system. FcRn binds to the Fc region of monomeric immunoglobulins gamma, mediates the uptake of IgG from milk,Possible role in transfer of immunoglobulin G from mother to fetus. A principal component of antibody transport is the neonatal receptor for the Fc portion of immunoglobulin, a heterodimer of a MHC-1 alpha-chain homolog ( FcRn ) and beta-2-microglobulin ( B2M ).

Produkteigenschaften

• Molekulargewicht: 31.2&11.7 KDa
• NCBI: 61769
• Reinheit: Greater than 95% as determined by reducing SDS-PAGE

Anwendungsbeschreibung

• Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.