Recombinant Human IL-10RB (C-Fc)

Artikelnummer: EKL-PHH0860
Artikelname: Recombinant Human IL-10RB (C-Fc)
Artikelnummer: EKL-PHH0860
Hersteller Artikelnummer: PHH0860
Alternativnummer: EKL-PHH0860-10UG,EKL-PHH0860-50UG,EKL-PHH0860-500UG
Hersteller: EnkiLife
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Alternative Synonym: Interleukin-10 receptor subunit beta(IL10RB),Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2,
Interleukin-10 receptor subunit beta(IL10RB), also known as Cytokine receptor class-II member 4,Cytokine receptor family 2 member 4,Interleukin-10 receptor subunit 2, belongs to the type II cytokine receptor family. IL10RB is a single- pass type I membrane protein and contains two fibronectin type-III domains. It is an accessory chain which is essential for the active interleukin 10 receptor complex. Coexpression of IL10RB and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Defects in IL10RB are the cause of inflammatory bowel disease type 25 (IBD25) which is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology.
Molekulargewicht: 50.6 KDa
NCBI: 08334
Reinheit: Greater than 95% as determined by reducing SDS-PAGE
Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.