Recombinant Human NgR (C-6His)

Artikelnummer: EKL-PHH1236
Artikelname: Recombinant Human NgR (C-6His)
Artikelnummer: EKL-PHH1236
Hersteller Artikelnummer: PHH1236
Alternativnummer: EKL-PHH1236-10UG,EKL-PHH1236-50UG,EKL-PHH1236-500UG
Hersteller: EnkiLife
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Alternative Synonym: Reticulon-4 Receptor, Nogo Receptor, NgR, Nogo-66 Receptor, RTN4R, NOGOR
Nogo Receptor (NgR) is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the Nogo recptor family. Human NgR is predominantly expressed in neurons and their axons in the central nervous systems. As a receptor for myelin-derived proteins Nogo, myelin-associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (OMG), NgR mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. NgR may be proposed as a potential drug target for treatment of various neurological conditions. Additionally, NgR may play a role in regulating the function of gap junctions.
Molekulargewicht: 46.32 KDa
NCBI: 9
Reinheit: Greater than 95% as determined by reducing SDS-PAGE
Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.