Recombinant Human TNF RII (174AA,C-6His)

Artikelnummer: EKL-PHH1687
Artikelname: Recombinant Human TNF RII (174AA,C-6His)
Artikelnummer: EKL-PHH1687
Hersteller Artikelnummer: PHH1687
Alternativnummer: EKL-PHH1687-10UG,EKL-PHH1687-50UG,EKL-PHH1687-500UG
Hersteller: EnkiLife
Wirt: Human
Kategorie: Proteine/Peptide
Spezies Reaktivität: Human
Alternative Synonym: Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor
Tumor necrosis factor receptor superfamily member 1B(TNFRSF1B) is expressed by the gene TNFRSF1B. The soluble form is produced from the membrane form by proteolytic processing. It can bind to TRAF2, and interacts with BMX. It can act as the receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha.
Molekulargewicht: 19 KDa
NCBI: 20333
Reinheit: Greater than 95% as determined by reducing SDS-PAGE
Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.