Recombinant Human Siglec-7 (C-6His)

Produktübersicht

• Artikelname: Recombinant Human Siglec-7 (C-6His)
• Artikelnummer: EKL-PHH2081
• Hersteller Artikelnummer: PHH2081
• Alternativnummer: EKL-PHH2081-10UG,EKL-PHH2081-50UG,EKL-PHH2081-500UG
• Hersteller: EnkiLife
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Human
• Alternative Synonym: siglec-7, AIRM1, AIRM-1, AIRM1QA79 membrane protein, CD328 antigen, CD328, CDw328, D-siglec, p75, p75/AIRM1, QA79, sialic acid binding Ig-like lectin 7, sialic acid-binding Ig-like lectin 7, Siglec7, Siglec-7

Produktbeschreibung

Siglecs (sialic acid binding Ig-like lectins) are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Eleven human Siglecs have been cloned and characterized. Human Siglec-7 encodes a 467 amino acid (aa) polypeptide with a hydrophobic signal peptide, an N-terminal Ig-like V-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail. Siglec-7 exists as a monomer on the cell surface and is expressed on natural killer cells, CD8+ T cells and monocytes. It binds equally well to both alpha 2,3- and alpha 2,6-linked sialic acid. The gene encoding Siglec-7 was mapped to chromosome 19q13.3.

Produkteigenschaften

• Molekulargewicht: 37.8 KDa
• NCBI: 9
• Reinheit: Greater than 95% as determined by reducing SDS-PAGE

Anwendungsbeschreibung

• Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.