Recombinant Mouse IL-12B (C-6His), Human

Produktübersicht

• Artikelname: Recombinant Mouse IL-12B (C-6His), Human
• Artikelnummer: EKL-PHM0983
• Hersteller Artikelnummer: PHM0983
• Alternativnummer: EKL-PHM0983-10UG,EKL-PHM0983-50UG,EKL-PHM0983-500UG
• Hersteller: EnkiLife
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Alternative Synonym: Interleukin-12 subunit beta, IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40, Il12b

Produktbeschreibung

Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

Produkteigenschaften

• Molekulargewicht: 36.8 KDa
• NCBI: 43432
• Reinheit: Greater than 95% as determined by reducing SDS-PAGE

Anwendungsbeschreibung

• Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.