Recombinant Mouse PDGFRA (C-6His), Human

Produktübersicht

• Artikelname: Recombinant Mouse PDGFRA (C-6His), Human
• Artikelnummer: EKL-PHM1288
• Hersteller Artikelnummer: PHM1288
• Alternativnummer: EKL-PHM1288-10UG,EKL-PHM1288-50UG,EKL-PHM1288-500UG
• Hersteller: EnkiLife
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Mouse
• Alternative Synonym: Platelet-derived growth factor receptor alpha, PDGF-R-alpha, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140a, Pdgfra

Produktbeschreibung

Platelet-derived growth factor receptors (PDGFR) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-alpha and -beta. These two receptor isoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -alphaalpha, -betabeta and -alphabeta. PDGFRalpha and PDGFRbeta are members of the class III RTK family. Inappropriate PDGFRalpha and PDGFRbeta signaling has been linked to a number of proliferative disorders.

Produkteigenschaften

• Molekulargewicht: 56.9 KDa
• NCBI: 26618
• Reinheit: Greater than 95% as determined by reducing SDS-PAGE

Anwendungsbeschreibung

• Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.