Recombinant Cynomolgus LAG-3 (C-Fc), Human

Produktübersicht

• Artikelname: Recombinant Cynomolgus LAG-3 (C-Fc), Human
• Artikelnummer: EKL-PHV1953
• Hersteller Artikelnummer: PHV1953
• Alternativnummer: EKL-PHV1953-10UG,EKL-PHV1953-50UG,EKL-PHV1953-500UG
• Hersteller: EnkiLife
• Wirt: Human
• Kategorie: Proteine/Peptide
• Spezies Reaktivität: Monkey
• Alternative Synonym: Lymphocyte activation gene 3 protein, LAG3, LAG-3, Protein FDC, CD223

Produktbeschreibung

Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling. It can lead to increased antigen-specific T-cell responses in vivo. LAG-3 has higher affinity to MHC class II than CD4.

Produkteigenschaften

• Molekulargewicht: 73.6 KDa
• NCBI: 005570011
• Reinheit: Greater than 95% as determined by reducing SDS-PAGE

Anwendungsbeschreibung

• Anwendungsbeschreibung: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.