Anthracycline anticancer antibiotic. Induces DNA damage by intercalating into DNA and inhibiting topoisomerase I and II. Inhibits RNA and DNA synthesis. Induces DNA single strand breaks and apoptosis in tumor cells.
Molekulargewicht:
527.5 . 36.5
Quelle:
Isolated from Streptomyces spec.
Reinheit:
90% (Assay)
CAS Nummer:
[23541-50-6]
Formel:
C27H29NO10 . HCl
Target-Kategorie:
Topoisomerase I, Topoisomerase II
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