17-AAG is a less toxic and more stable analog of geldanamycin. It is an HSP90 inhibitor that displays a 100-fold higher affinity for HSP90 derived from tumor cells compared to HSP90 from normal cells. 17-AAG inhibits Akt activation and expression in tumo
Molekulargewicht:
585.7
Quelle:
Semisynthetic derivative from geldanamycin.
Reinheit:
98% (TLC)
CAS Nummer:
[75747-14-7]
Formel:
C31H43N3O8
Target-Kategorie:
HSP90
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