A topoisomerase II inhibitor that does not cause DNA damage. Induces apoptosis in several cell lines including K562 and Molt-4 cells. Induces a G2 checkpoint that is associated with an ATR-dependent inhibition of polo-like kinase 1 (plk1) activity and a
Molekulargewicht:
282.3
Reinheit:
95% (HPLC)
CAS Nummer:
[21416-68-2]
Formel:
C12H18N4O4
Target-Kategorie:
Topoisomerase II
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