A-803467 is a potent and selective inhibitor of the TTX-resistant voltage-gated sodium channel Nav1.8 which is preferentially expressed on sensory neurons. IC50 for human Nav1.8=8.0 nM (140 nM for rat). It attenuates neuropathic and inflammatory pain in
Molekulargewicht:
357.8
Quelle:
Synthetic.
Reinheit:
98% (TLC)
CAS Nummer:
[944261-79-4]
Formel:
C19H16ClNO4
Target-Kategorie:
Voltage-gated sodium channel subunit alpha Nav1.8
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