Antagonizes Wnt/beta-catenin/Tcf-mediated transcription as well as PPARgamma and delta activity. Able to inhibit the recruitment of the co-activators beta-catenin and GRIP1, both of which are activators for both pathways. FH535 was toxic (LC50=5 to 15µM) to 10 of 12 c
Molekulargewicht:
361.2
Reinheit:
98% (TLC)
CAS Nummer:
[108409-83-2]
Formel:
C13H10Cl2N2O4S
Target-Kategorie:
Wnt
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